Παρακαλώ χρησιμοποιήστε αυτό το αναγνωριστικό για να παραπέμψετε ή να δημιουργήσετε σύνδεσμο προς αυτό το τεκμήριο:
https://hdl.handle.net/123456789/1070| Τύπος: | Άρθρο σε επιστημονικό περιοδικό |
| Τίτλος: | Size-dependent in vitro inhalation bioaccessibility of PAHs and O/N PAHs: implications to inhalation risk assessment |
| Συγγραφέας: | [EL] Μπέσης, Αθανάσιος[EN] Besis, Athanasios [EL] Γάλλου, Δομνίκη[EN] Gallou, Domniki [EL] Αυγενικού, Αννα[EN] Avgenikou, Anna [EL] Σεραφείμ, Ελένη[EN] Serafeim, Eleni [EL] Σαμαρά - Κωνσταντίνου, Κωνσταντίνη[EN] Samara - Konstantinou Constantini |
| Ημερομηνία: | 22/02/2022 |
| Περίληψη: | Size segregated samples (<0.49, 0.49-0.95, 0.95-1.5, 1.5-3.0, 3.0-7.2 and >7.2 μm) of atmospheric particulate matter (APM) were collected at a traffic site in the urban agglomeration of Thessaloniki, northern Greece, during the cold and the warm period of 2020. The solvent-extractable organic matter was analyzed for selected organic contaminants including polycyclic aromatic hydrocarbons (PAHs), and their nitro- and oxy-derivarives (NPAHs and OPAHs, respectively). Mean concentrations of ∑16PAHs, ∑6NPAHs and ∑10OPAHs associated to total suspended particles (TSP) were 18 ng m-3, 0.2 ng m-3 and 0.9 ng m-3, respectively, in the cold period exhibiting significant decrease (6.4, 0.2 and 0.09 ng m-3, respectively) in the warm period. The major amount of all compounds was found to be associated with the alveolar particle size fraction <0.49μm. The inhalation bioaccessibility of PAHs and O/N PAHs was measured in vitro using two simulated lung fluids (SLFs), the Gamble’s solution (GS) and the artificial lysosomal fluid (ALF). With both SLFs, the derived bioaccessible fractions (BAFs) followed the order PAHs > OPAHs > NPAHs. Although no clear dependence of bioaccessibility on particle size was obtained, increased bioaccessibility of PAHs and PAH derivatives in coarse particles (>7.2 μm) was evident. Bioaccessibility was found to be strongly related to the logKOW and the water solubility of individual compounds hindering limited mobilization of the most hydrophobic and less water-soluble compounds from APM to SLFs. The lifetime cancer risk due to inhalation exposure to bioaccessible PAHs, NPAHs and OPAHs was estimated and compared to those calculated from the particulate concentrations of organic contaminants. |
| Γλώσσα: | Αγγλικά |
| Σελίδες: | 11 |
| DOI: | 10.1016/j.envpol.2022.119045 |
| ISSN: | 0269-7491 |
| Θεματική κατηγορία: | [EL] Περιβαλλοντική χημεία[EN] Environmental Chemistry |
| Λέξεις-κλειδιά: | PAHs; OPAHs; NPAHs; Size distribution; Bioaccessibility |
| Κάτοχος πνευματικών δικαιωμάτων: | © 2022 Elsevier Ltd. All rights reserved. |
| Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη: | https://www.sciencedirect.com/science/article/pii/S0269749122002597 |
| Ηλεκτρονική διεύθυνση περιοδικού: | https://www.sciencedirect.com/journal/environmental-pollution |
| Τίτλος πηγής δημοσίευσης: | Environmental Pollution |
| Τόμος: | 301 |
| Σελίδες τεκμηρίου (στην πηγή): | Article no 119045 |
| Σημειώσεις: | This research is co-financed by Greece and the European Union (European Social Fund- ESF) through the Operational Programme « Human Resources Development, Education and Lifelong Learning» in the context of the project “Reinforcement of Postdoctoral Researchers - 2nd Cycle” (MIS-5033021), implemented by the State Scholarships Foundation (ІΚΥ). |
| Εμφανίζεται στις συλλογές: | Μεταδιδακτορικοί ερευνητές |
Αρχεία σε αυτό το τεκμήριο:
| Αρχείο | Περιγραφή | Σελίδες | Μέγεθος | Μορφότυπος | Έκδοση | Άδεια | |
|---|---|---|---|---|---|---|---|
| PU25.pdf Restricted Access | Size-dependent in vitro inhalation bioaccessibility of PAHs and O/N PAHs - Implications to inhalation risk assessment | 2.75 MB | Adobe PDF | - |  | Δείτε/ανοίξτε |