1. Αποθετήριο Παραδοτέων Υποτρόφων Δράσεων ΕΣΠΑ Τριτοβάθμιας Εκπαίδευσης 2017-2023
2. Όλο το Αποθετήριο
3. Ερευνητικές ομάδες

Τύπος:	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Paper-based device for sweat chloride testing based on the photochemical response of silver halide nanocrystals
Συγγραφέας:	[EL] Χολέβα, Τατιάνα[EN] Choleva, Tatiana [EL] Ματιάκη Χριστίνα[EN] Matiaki, Christina [EL] Σφακιανάκη, Αφροδίτη[EN] Sfakianaki, Afroditi [EL] Βλεσσίδης, Αθανάσιος[EN] Vlessidis, Athanasios [EL] Γκιώκας, Δημοσθένης[EN] Giokas, Dimosthenis
Ημερομηνία:	08/10/2021
Περίληψη:	A new method for the determination of chloride anions in sweat is described. The novelty of the method relies on the different photochemical response of silver ions and silver chloride crystals when exposed to UV light. Silver ions undergo an intense colorimetric transition from colorless to dark grey-brown due to the formation of nanosized Ag while AgCl exhibits a less intense color change from white to slightly grey. The analytical signal is obtained as mean grey value of color intensity on the paper surface and is expressed as the absolute difference between the signal of the blank (i.e., in absence of chloride) and the sample (i.e., in the presence of chloride). The method is simple to perform (addition of sample, incubation in the absence of light, irradiation, and offline measurement in a flatbed scanner), does not require any special signal processing steps (the color intensity is directly measured from a constant window on the paper surface without any imager processing) and is performed with minimum sample volume (2 μL). The method operates within a large chloride concentration range (10–140 mM) with good detection limits (2.7 mM chloride), satisfactory recoveries (95.2–108.7%), and reproducibility (<9%). Based on these data the method could serve as a potential tool for the diagnosis of cystic fibrosis through the determination of chloride in human sweat.
Γλώσσα:	Αγγλικά
Σελίδες:	12
DOI:	10.3390/chemosensors9100286
EISSN:	2227-9040
Θεματική κατηγορία:	[EL] Αναλυτική χημεία[EN] Analytical Chemistry
Λέξεις-κλειδιά:	sweat testing; cystic fibrosis; paper-based devices; silver halides; photoreduction; point-of-care diagnostics
Κάτοχος πνευματικών δικαιωμάτων:	© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Όροι και προϋποθέσεις δικαιωμάτων:	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη:	https://www.mdpi.com/2227-9040/9/10/286
Ηλεκτρονική διεύθυνση περιοδικού:	https://www.mdpi.com/journal/chemosensors
Τίτλος πηγής δημοσίευσης:	Chemosensors
Τεύχος:	10
Τόμος:	9
Σελίδες τεκμηρίου (στην πηγή):	Article no 286
Σημειώσεις:	This research was co-financed by Greece and the European Union (European Social FundESF) through the Operational Programme “Human Resources Development, Education and Lifelong Learning 2014-2020” in the context of the project “Development of novel analytical methods and signal transduction techniques for the optical analysis of biomarkers in biological fluids using common imaging devices” (MIS 5047630).
Εμφανίζεται στις συλλογές:	Ερευνητικές ομάδες