1. Αποθετήριο Παραδοτέων Υποτρόφων Δράσεων ΕΣΠΑ Τριτοβάθμιας Εκπαίδευσης 2017-2023
2. Όλο το Αποθετήριο
3. Ερευνητικές ομάδες

Τύπος:	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	The relation of clinic and ambulatory BP with the risk of cardiovascular events and all-cause mortality among patients on peritoneal dialysis
Συγγραφέας:	[EL] Γεωργιανός, Παναγιώτης[EN] Georgianos, Panagiotis [EL] Βάιος, Βασίλειος[EN] Vaios, Vasileios [EL] Ζεμπεκάκης, Παντελής[EN] Zebekakis, Pantelis [EL] Λιακόπουλος, Βασίλειος[EN] Liakopoulos, Vassilios
Ημερομηνία:	21/05/2021
Περίληψη:	Large observational studies showed a U-shaped association of clinic blood pressure (BP) with mortality among patients undergoing peritoneal dialysis (PD). Whether ambulatory BP provides a more direct risk signal in this population remains unknown. In a prospective cohort of 108 PD patients, standardized clinic BP was recorded at baseline with the validated device HEM-705 (Omron, Healthcare, Bannockburn, IL, USA) and 24-h ambulatory BP monitoring was performed using the Mobil-O-Graph monitor (IEM, Stolberg, Germany). Over a median follow-up of 16 months (interquartile range: 19 months), 47.2% of the overall population reached the composite outcome of non-fatal myocardial infarction, non-fatal stroke, or all-cause death. In Cox-regression analysis, systolic but not diastolic BP was prognostically informative. Compared with the reference quartile 1 of 24-h systolic BP (SBP), the multivariate-adjusted hazard ratio for the composite outcome was 1.098 (95% confidence interval (CI): 0.434–2.777) in quartile 2, 1.004 (95% CI: 0.382–2.235) in quartile 3 and 2.449 (95% CI: 1.156–5.190) in quartile 4. In contrast, no such association was observed between increasing quartiles of clinic SBP and composite outcome. The present study shows that among PD patients, increasing ambulatory SBP is independently associated with higher risk of adverse cardiovascular events and mortality, providing superior prognostic information than standardized clinic SBP.
Γλώσσα:	Αγγλικά
Σελίδες:	10
DOI:	10.3390/jcm10112232
EISSN:	2077-0383
Θεματική κατηγορία:	[EL] Επιδημιολογία[EN] Epidemiology
Λέξεις-κλειδιά:	peritoneal dialysis; blood pressure; mortality; ambulatory BP; cardiovascular events; clinic BP
Κάτοχος πνευματικών δικαιωμάτων:	© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
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Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη:	https://www.mdpi.com/2077-0383/10/11/2232
Ηλεκτρονική διεύθυνση περιοδικού:	https://www.mdpi.com/journal/jcm
Τίτλος πηγής δημοσίευσης:	Journal of Clinical Medicine
Τεύχος:	11
Τόμος:	10
Σελίδες τεκμηρίου (στην πηγή):	Article no 2232
Σημειώσεις:	This research is co-financed by Greece and the European Union (European Social Fund- ESF) through the Operational Programme «Human Resources Development, Education and Lifelong Learning 2014-2020» in the context of the project “A study on the association of clinic, home and ambulatory blood pressure with cardiovascular morbidity and mortality in patients receiving long-term peritoneal dialysis” (MIS: 5047882).
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