1. Αποθετήριο Παραδοτέων Υποτρόφων Δράσεων ΕΣΠΑ Τριτοβάθμιας Εκπαίδευσης 2017-2023
2. Όλο το Αποθετήριο
3. Μεταδιδακτορικοί ερευνητές

Τύπος:	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Could the 2010 HIV outbreak in Athens, Greece have been prevented? A mathematical modeling study
Συγγραφέας:	[EL] Γκούντας, Ηλίας[EN] Gountas, Ilias [EL] Νικολόπουλος, Γεώργιος[EN] Nikolopoulos, Georgios [EL] Τουλούμη, Γιώτα[EN] Touloumi, Giota [EL] Φωτίου, Αναστάσιος[EN] Fotiou, Anastasios [EL] Σουλιώτης, Κυριάκος[EN] Souliotis, Kyriakos
Ημερομηνία:	07/10/2021
Περίληψη:	Introduction In 2009 and 2010, Athens, Greece experienced a hepatitis C virus (HCV) and a Human Immunodeficiency Virus (HIV) outbreak among People Who Inject Drugs (PWID), respectively. The HCV outbreak was not detected, while that of HIV was identified in 2011. The integrated HIV-interventions, launched in early 2012, managed to reduce directly the HIV incidence and indirectly the HCV incidence. This study aims to assess what would have been the course of the HIV outbreak and its associated economic consequences if the 2009 HCV outbreak had been detected and integrated interventions had been initiated 1- or 2-years earlier. Methods The model was calibrated to reproduce the observed HIV epidemiological and clinical parameters among PWID of Athens, Greece. We examined the effect of the 1- or 2-years earlier detection scenarios, the 1-year later detection, the non-detection scenario, and compared them to the status quo scenario. Results Cumulative HIV cases, under the status-quo scenario during 2009‐2019, were 1360 (90% Credible intervals: 290, 2470). If the HCV outbreak had been detected 1- or 2- years earlier, with immediate initiation of integrated interventions, 740 and 1110 HIV cases could be averted by 2019, respectively. Regarding the costs, if there was an efficient notification system to detect the HCV outbreak 1 or 2 years earlier, 35.2–53.2 million euros could be saved compared to the status quo by 2019. Conclusions If the HCV outbreak had been detected and promptly addressed, the HIV outbreak would have been prevented and 35.2–53.2 million euros could have been saved.
Γλώσσα:	Αγγλικά
Σελίδες:	13
DOI:	10.1371/journal.pone.0258267
EISSN:	1932-6203
Θεματική κατηγορία:	[EL] Επιδημιολογία[EN] Epidemiology
Κάτοχος πνευματικών δικαιωμάτων:	© The Author(s) 2021.
Όροι και προϋποθέσεις δικαιωμάτων:	This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη:	https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0258267
Ηλεκτρονική διεύθυνση περιοδικού:	https://journals.plos.org/plosone/
Τίτλος πηγής δημοσίευσης:	PLOS one
Τεύχος:	10
Τόμος:	16
Σελίδες τεκμηρίου (στην πηγή):	Article no e0258267
Σημειώσεις:	IG research is co-financed by Greece and the European Union (European Social Fund- ESF) through the Operational Programme “Human Resources Development, Education and Lifelong Learning” in the context of the project “Reinforcement of Postdoctoral Researchers - 2nd Cycle” (MIS-5,033,021), implemented by the State Scholarships Foundation (IKY).
Εμφανίζεται στις συλλογές:	Μεταδιδακτορικοί ερευνητές