1. Αποθετήριο Παραδοτέων Υποτρόφων Δράσεων ΕΣΠΑ Τριτοβάθμιας Εκπαίδευσης 2017-2023
2. Όλο το Αποθετήριο
3. Μεταδιδακτορικοί ερευνητές

Τύπος:	Αναρτημένη ανακοίνωση (poster)
Τίτλος:	Greek MSM: 95-95-95 target is not enough to meet the HIV incidence reduction goal
Συγγραφέας:	[EL] Γκούντας, Ηλίας[EN] Gountas, Ilias [EL] Σουλιώτης, Κυριάκος[EN] Souliotis, Kyriakos [EL] Νικολόπουλος, Γεώργιος[EN] Nikolopoulos, Georgios [EL] Τουλούμη, Γιώτα[EN] Touloumi, Giota
Ημερομηνία:	Φεβ-2022
Περίληψη:	The 95-95-95 strategy aims to end the AIDS epidemic by 2030 by diagnosing 95% of all people living with HIV (PLHIV), by administering antiretroviral therapy (ART) to 95% of the diagnosed, and by achieving viral suppression (VS) on 95% of those on ART. UNAIDS modeling predictions suggest that those targets could reduce the HIV incidence worldwide by 90% in 2030 compared to 2010. However, several studies have underlined that in high-income countries, HIV cascade of care (CoC) targets may be insufficient to achieve the incidence goal and that additional interventions, like pre-exposure prophylaxis (PrEP), will be needed. In Greece, HIV infection is more prevalent among men who have sex with men (MSM), accounting for about half of all annual diagnoses. This study aims: a) to estimate the expected reduction in HIV incidence under the status quo scenario by 2030 and b) to highlight the required healthcare interventions to achieve the UNAIDS incidence goal by 2030. A previously published stochastic, dynamic mathematical model was used to simulate HIV transmission among MSM1. The population was stratified by risk behaviours according to the Greek EMIS study (high=15.1%/medium=28.7%/low=56.2%). The model was calibrated to match the trajectories of the Greek HIV CoC in the years 2013, 2016, 2019, and 2020. The infection rate, the probability of being diagnosed, and the probability of ART initiation were varied until the model reproduced the observed HIV epidemic of Greece. We examined the effect of the status quo scenario and the HIV elimination scenario. The model showed that although the MSM PLHIV could reach the 95-95-95 target in 2030, this would not be enough to achieve the 90% reduction in HIV incidence (estimated reduction of 32.4% in 2030 compared to 2010). Launching a PrEP intervention only for the high-risk MSM, without any other interventions, would cause a modest incidence reduction (58% in 2030 compared to 2010). To achieve HIV elimination in 2030, the 95-95-95 target should be achieved, all high-risk MSM should be on PrEP, and primary prevention (e.g., full condom use) among medium-risk MSM with the target to be moved from medium to low-risk should be implemented (Figure). Reaching the 95-95-95 CoC targets among MSM in Greece is not enough. To achieve HIV elimination, PrEP delivery to high-risk MSM, and primary preventions among medium-risk MSM should be implemented.
Γλώσσα:	Αγγλικά
Τόπος δημοσίευσης:	Virtually
Σελίδες:	1
Θεματική κατηγορία:	[EL] Επιδημιολογία[EN] Epidemiology
Κάτοχος πνευματικών δικαιωμάτων:	© The Author(s) 2022
Όροι και προϋποθέσεις δικαιωμάτων:	CROI conference materials (eg, the conference program, Abstract eBook, electronic posters, CROI logo, etc) are protected by copyright. Permission to replicate or reproduce these elements, in whole or in part, must be obtained from the CROI Conference Manager, the International Antiviral Society-USA (IAS-USA). Study data (including figures within abstracts or electronic posters) are the property of the study authors. Permission to use data and figures cannot be given by IAS–USA unless it is for regulatory reasons. For more information, please email CROIabstracts@iasusa.org.
Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη:	https://www.croiconference.org/abstract/greek-msm-95-95-95-target-is-not-enough-to-meet-the-hiv-incidence-reduction-goal/
Ηλεκτρονική διεύθυνση περιοδικού:	https://www.croiconference.org/search-abstracts/
Τίτλος πηγής δημοσίευσης:	CROI 2022 Conference Abstracts
Σελίδες τεκμηρίου (στην πηγή):	Abstract no 797
Όνομα εκδήλωσης:	CROI 2022 Conference
Τοποθεσία εκδήλωσης:	Virtual Conference
Ημ/νία έναρξης εκδήλωσης:	12/02/2022
Ημ/νία λήξης εκδήλωσης:	16/02/2022
Σημειώσεις:	IG was co-financed by Greece and the European Union (European Social Fund- ESF) through the Operational Programme “Human Resources Development, Education and Lifelong Learning” in the context of the project “Reinforcement of Postdoctoral Researchers - 2 nd Cycle” (MIS-5,033,021), implemented by the State Scholarships Foundation (IKY)
Εμφανίζεται στις συλλογές:	Μεταδιδακτορικοί ερευνητές