Παρακαλώ χρησιμοποιήστε αυτό το αναγνωριστικό για να παραπέμψετε ή να δημιουργήσετε σύνδεσμο προς αυτό το τεκμήριο:
https://hdl.handle.net/123456789/1519| Τύπος: | Άρθρο σε επιστημονικό περιοδικό |
| Τίτλος: | Fish scales produce cortisol upon stimulation with ACTH |
| Συγγραφέας: | [EL] Σαμαράς, Αθανάσιος[EN] Samaras, Athanasios [EL] Παυλίδης, Μιχαήλ[EN] Pavlidis, Michail |
| Ημερομηνία: | 12/12/2022 |
| Περίληψη: | Cortisol concentration in fish scales is a novel and reliable indicator of chronic stress. However, until now cortisol in scales has been considered to be accumulated through the circulation and it has not yet been studied whether it can be de novo produced from cells found in the scales. In the current study, scales of European sea bass, Dicentrarchus labrax, were stimulated in-vitro with a range of concentrations of adrenocorticotropic hormone (ACTH) to investigate if they can produce and release cortisol. Moreover, scales were exposed to a combination of ACTH and metyrapone, an inhibitor of cortisol production, to examine whether cortisol was actually produced in the scales. Results from ACTH administration showed that scales increased their cortisol release in a dose-dependent manner. This effect was reversed when scales were co-incubated with ACTH and metyrapone, indicating that cortisol was produced de novo and not released only upon stimulation with ACTH. |
| Γλώσσα: | Αγγλικά |
| Σελίδες: | 8 |
| DOI: | 10.3390/ani12243510 |
| EISSN: | 2076-2615 |
| Θεματική κατηγορία: | [EL] Άλλες Γεωπονικές επιστήμες[EN] Other agricultural sciences |
| Λέξεις-κλειδιά: | adrenocorticotropic hormone; Cortisol; Chronic stress; in-vitro stimulation; Fish; scales |
| Κάτοχος πνευματικών δικαιωμάτων: | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. |
| Όροι και προϋποθέσεις δικαιωμάτων: | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/) |
| Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη: | https://www.mdpi.com/2076-2615/12/24/3510 |
| Ηλεκτρονική διεύθυνση περιοδικού: | https://www.mdpi.com/journal/animals |
| Τίτλος πηγής δημοσίευσης: | Animals |
| Τεύχος: | 24 |
| Τόμος: | 12 |
| Σελίδες τεκμηρίου (στην πηγή): | Article no 3510 |
| Σημειώσεις: | This research was co-financed by Greece and the European Union (European Social FundESF) through the Operational Programme «Human Resources Development, Education and Lifelong Learning» in the context of the project “Reinforcement of Postdoctoral Researchers-2nd Cycle” (MIS-5033021), implemented by the State Scholarships Foundation (IKΥ). This research was also co-funded by Greece and the European Union via the Operational Programmes “Competitiveness, Entrepreneurship & Innovation (EPAnEK)” (T6ΥBΠ-00317) and “Fisheries and Maritime 2014–2020” (EPALTH 2014–2020) (MIS-5010690). |
| Εμφανίζεται στις συλλογές: | Μεταδιδακτορικοί ερευνητές |
Αρχεία σε αυτό το τεκμήριο:
| Αρχείο | Περιγραφή | Σελίδες | Μέγεθος | Μορφότυπος | Έκδοση | Άδεια | |
|---|---|---|---|---|---|---|---|
| 20_Samaras&Pavlidis2022_Cortisol synthesis and release from fish scales.pdf | 887.89 kB | Adobe PDF | - |  | Δείτε/ανοίξτε |