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https://hdl.handle.net/123456789/287| Τύπος: | Άρθρο σε επιστημονικό περιοδικό |
| Τίτλος: | Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease |
| Συγγραφέας: | [EL] Μαράκη, Μαρία[EN] Maraki, Maria [EL] Γιαννακούλια, Μαρία[EN] Yannakoulia, Mary [EL] Σταμέλου, Μαρία[EN] Stamelou, Maria [EL] Στεφανής, Λεωνίδας[EN] Stefanis, Leonidas Xiromerisiou, Georgia [EL] Κοσμίδου, Μαρία-Ελένη[EN] Kosmidis Mary-Helen Dardiotis, Efthimios [EL] Χατζηγεωργίου, Γεώργιος[EN] Hadjigeorgiou, Georgios [EL] Σακκά, Παρασκευή[EN] Sakka, Paraskevi [EL] Αναστάσιου, Κωνσταντίνος Simopoulou, Eleni [EL] Σκαρμέας, Νικόλαος[EN] Scarmeas, Nikolaos |
| Ημερομηνία: | 29/03/2018 |
| Περίληψη: | Backgound: The Movement Disorders Society (MDS) recently introduced a methodology for probability score calculation for prodromal PD. Objectives: To assess the probability of prodromal PD in an older population and to investigate its possible association with Mediterranean diet adherence. Methods: Data from a population-based cohort study of older adults (HEllenic Longitudinal Investigation of Aging and Diet–HELIAD) in Greece were used. Probability of prodromal PD was calculated according to MDS research criteria. A detailed food frequency questionnaire was used to evaluate dietary intake and calculate Mediterranean diet adherence score, ranging from 0 to 55, with higher scores indicating higher adherence. Results: The median probability of prodromal PD was 1.9%, ranging from 0.2 to 96.7% in 1731 PD-free individuals over the age of 65 (41% male). Lower probability for prodromal PD (p<0.001) in the higher Mediterranean diet adherence groups was noted, driven mostly by non-motor markers of prodromal PD, depression, constipation, urinary dysfunction and daytime somnolence. Each unit increase in the Mediterranean diet score was associated with a 2% decreased probability for prodromal PD (p<0.001). Compared to participants in the lowest quartile of Mediterranean diet adherence, those in the highest quartile were associated with a ~21% lower probability for prodromal PD. Conclusions: Adherence to the Mediterranean diet is associated with lower probability of prodromal PD in older people. Further studies are needed to elucidate the potential causality of this association, potential relation of the Mediterranean diet to delayed onset or lower incidence of PD, as well as the underlying neurobiological mechanisms. |
| Γλώσσα: | Αγγλικά |
| Σελίδες: | 10 |
| DOI: | 10.1002/mds.27489 |
| EISSN: | 1531-8257 |
| Θεματική κατηγορία: | [EL] Διατροφή και Διαιτολογία[EN] Nutrition and Dietetics [EL] Ιατρική και Επιστήμες Υγείας[EN] Medical and Health Sciences [EL] Νευροεπιστήμες[EN] Neurosciences |
| Λέξεις-κλειδιά: | elderly; Mediterranean; neurodegeneration; nutrition; prodromal |
| Κάτοχος πνευματικών δικαιωμάτων: | © 2018 International Parkinson and Movement Disorder Society |
| Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη: | https://onlinelibrary.wiley.com/doi/10.1002/mds.27489 |
| Ηλεκτρονική διεύθυνση περιοδικού: | https://onlinelibrary.wiley.com/journal/15318257 |
| Τίτλος πηγής δημοσίευσης: | Movement Disorders |
| Τεύχος: | 1 |
| Τόμος: | 34 |
| Σελίδες τεκμηρίου (στην πηγή): | 48-57 |
| Σημειώσεις: | This study was supported by the following grants: IIRG‐09‐133014 from the Alzheimer's Association; 189 10276/8/9/2011 from the ESPA‐EU program Excellence Grant (ARISTEIA), which is co‐funded by the European Social Fund and Greek National resources, and DY2b/oik.51657/14.4.2009 from the Ministry for Health and Social Solidarity (Greece). Maria I. Maraki and Costas A. Anastasiou have received financial support from the Greek State Scholarships Foundation (MIS: 5001552). |
| Εμφανίζεται στις συλλογές: | Μεταδιδακτορικοί ερευνητές |
Αρχεία σε αυτό το τεκμήριο:
| Αρχείο | Περιγραφή | Σελίδες | Μέγεθος | Μορφότυπος | Έκδοση | Άδεια | |
|---|---|---|---|---|---|---|---|
| 4.Maraki et al. Movement Disorders, Vol. 34, No. 1, 2019.pdf Restricted Access | 10 σελίδες σελίδες | 352.12 kB | Adobe PDF | Δημοσιευμένη/του Εκδότη |  | Δείτε/ανοίξτε |