1. Αποθετήριο Παραδοτέων Υποτρόφων Δράσεων ΕΣΠΑ Τριτοβάθμιας Εκπαίδευσης 2017-2023
2. Όλο το Αποθετήριο
3. Ερευνητικές ομάδες

Τύπος:	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Dataset of targeted metabolite analysis for five taxanes of hellenic Taxus baccata L. populations
Συγγραφέας:	[EL] Δαλμάρη, Ελευθερία[EN] Dalmaris, Eleftheria [EL] Αβραμίδου, Ευαγγελία[EN] Avramidou, Evangelia [EL] Ξανθοπούλου, Αλίκη[EN] Xanthopoulou, Aliki [EL] Αραβανόπουλος, Φίλιππος[EN] Aravanopoulos, Filippos
Ημερομηνία:	06/03/2020
Περίληψη:	Novel primary sources of one of the world’s leading anticancer agent, paclitaxel, as well as of other antineoplastic taxanes such as 10-deacetylbaccatin-III, are needed to meet an increasing demand. Among the Taxus species the promise of Taxus baccata L. (European or English yew) has been documented. In this study, the metabolite analysis of two marginal T. baccata populations in Greece (Mt. Cholomon and Mt. Olympus), located at the southeastern edge of the species natural distribution, are being explored. A targeted liquid chromatography – mass spectrometry (LC-MS/MS) analysis was used to determine the content of 10-deacetylbaccatin III, baccatin III, 10-deacetyltaxol, paclitaxel and cephalomannine in the needles of each of the populations from three sampling periods (spring, summer and winter). This is the first survey to generate a taxane targeted metabolite data set, since it derives from Hellenic natural populations that have not been explored before. Furthermore, it has used an extensive sample design in order to evaluate chemodiversity at the population level. The analysis revealed significant levels of chemodiversity within and among the investigated populations and significant seasonal variation that could be exploited for the selection of superior germplasm native to Greece, for yew plantations and further exploitation which is necessary for the production of important taxanes.
Γλώσσα:	Αγγλικά
Τόπος δημοσίευσης:	Thessaloniki, Greece
Σελίδες:	6
DOI:	10.3390/data5010022
ISSN:	2306-5729
Θεματική κατηγορία:	[EL] Δασολογία[EN] Forestry
Λέξεις-κλειδιά:	Taxus baccata; Metabolites; LC-MS/MS; Taxanes; Yew
Κάτοχος πνευματικών δικαιωμάτων:	© 2020 by the authors. Licensee MDPI
Όροι και προϋποθέσεις δικαιωμάτων:	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη:	https://www.mdpi.com/2306-5729/5/1/22
Τίτλος πηγής δημοσίευσης:	Data
Τεύχος:	1
Τόμος:	5
Σημειώσεις:	Funding: This research is co-financed by Greece and the European Union (European Social Fund- ESF) through the Operational Program «Human Resources Development, Education and Lifelong Learning 2014-2020» in the context of the project “Genetics, epigenetics and metabolomic analysis of European yew (Taxus baccata) in order to select plant material for the production of taxol and other antineoplastic taxanes in Greece” (MIS 5004922)
Εμφανίζεται στις συλλογές:	Ερευνητικές ομάδες