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https://hdl.handle.net/123456789/1609| Τύπος: | Άρθρο σε επιστημονικό περιοδικό |
| Τίτλος: | Electric field distribution induced by TMS: differences due to anatomical variation |
| Εναλλακτικός τίτλος: | - |
| Συγγραφέας: | [EL] Τζηρίνη, Μαριέττα[EN] Tzirini, Marietta [EL] Χατζηκυριάκου, Ευαγγελία[EN] Chatzikyriakou, Evangelia [EL] Κούσκουρας, Κωνσταντίνος[EN] Kouskouras, Konstantinos [EL] Φόρογλου, Νικόλαος[EN] Foroglou, Nikolaos [EL] Σαμαράς, Θεόδωρος[EN] Samaras, Theodoros [EL] Κιμισκίδης, Βασίλειος[EN] Kimiskidis, Vasilios |
| Ημερομηνία: | 29/04/2022 |
| Περίληψη: | Transcranial magnetic stimulation (TMS) is a well-established technique for the diagnosis and treatment of neuropsychiatric diseases. The numerical calculation of the induced electric field (EF) distribution in the brain increases the efficacy of stimulation and improves clinical outcomes. However, unique anatomical features, which distinguish each subject, suggest that personalized models should be preferentially used. The objective of the present study was to assess how anatomy affects the EF distribution and to determine to what extent personalized models are useful for clinical studies. The head models of nineteen healthy volunteers were automatically segmented. Two versions of each head model, a homogeneous and a five-tissue anatomical, were stimulated by the model of a Hesed coil (H-coil), employing magnetic quasi-static simulations. The H-coil was placed at two standard stimulating positions per model, over the frontal and central areas. The results show small, but indisputable, variations in the EFs for the homogeneous and anatomical models. The interquartile ranges in the anatomical versions were higher compared to the homogeneous ones, indicating that individual anatomical features may affect the prediction of stimulation volumes. It is concluded that personalized models provide complementary information and should be preferably employed in the context of diagnostic and therapeutic TMS studies. |
| Γλώσσα: | Αγγλικά |
| Σελίδες: | 21 |
| DOI: | 10.3390/ app12094509 |
| EISSN: | 2076-3417 |
| Θεματική κατηγορία: | [EL] Νευροεπιστήμες[EN] Neurosciences [EL] Εφαρμοσμένη φυσική[EN] Applied Physics |
| Λέξεις-κλειδιά: | TMS; personalized treatment planning; EF modeling; anatomy; deep TMS |
| Κάτοχος πνευματικών δικαιωμάτων: | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. |
| Όροι και προϋποθέσεις δικαιωμάτων: | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/) |
| Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη: | https://www.mdpi.com/2076-3417/12/9/4509 |
| Ηλεκτρονική διεύθυνση περιοδικού: | https://www.mdpi.com/journal/applsci |
| Τίτλος πηγής δημοσίευσης: | Applied Sciences |
| Τεύχος: | 9 |
| Τόμος: | 12 |
| Σελίδες τεκμηρίου (στην πηγή): | Article no 4509 |
| Σημειώσεις: | This research was co-financed by Greece and the European Union (European Social Fund-ESF) through the Operational Programme ‘Human Resources Development, Education and Lifelong Learning 2014–2020′ in the context of the project ‘Mapping of the human primary motor cortex (M1) with navigated Transcranial Magnetic Stimulation (navigated TMS, n TMS): method optimization with advanced neurophysiological and computational techniques’ (MIS 5047847). |
| Εμφανίζεται στις συλλογές: | Ερευνητικές ομάδες |
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| Αρχείο | Περιγραφή | Σελίδες | Μέγεθος | Μορφότυπος | Έκδοση | Άδεια | |
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| Electric field distribution induced by TMS differences due to anatomical variation.pdf | 7.29 MB | Adobe PDF | Δημοσιευμένη/του Εκδότη |  | Δείτε/ανοίξτε |