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Τύπος: Άρθρο σε επιστημονικό περιοδικό
Τίτλος: Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease
Συγγραφέας: [EL] Μαράκη, Μαρία[EN] Maraki, Mariasemantics logo
[EL] Γιαννακούλια, Μαρία[EN] Yannakoulia, Marysemantics logo
[EL] Σταμέλου, Μαρία[EN] Stamelou, Mariasemantics logo
[EL] Στεφανής, Λεωνίδας[EN] Stefanis, Leonidassemantics logo
Xiromerisiou, Georgia
[EL] Κοσμίδου, Μαρία-Ελένη[EN] Kosmidis Mary-Helensemantics logo
Dardiotis, Efthimios
[EL] Χατζηγεωργίου, Γεώργιος[EN] Hadjigeorgiou, Georgiossemantics logo
[EL] Σακκά, Παρασκευή[EN] Sakka, Paraskevisemantics logo
[EL] Αναστάσιου, Κωνσταντίνοςsemantics logo
Simopoulou, Eleni
[EL] Σκαρμέας, Νικόλαος[EN] Scarmeas, Nikolaossemantics logo
Ημερομηνία: 29/03/2018
Περίληψη: Backgound: The Movement Disorders Society (MDS) recently introduced a methodology for probability score calculation for prodromal PD. Objectives: To assess the probability of prodromal PD in an older population and to investigate its possible association with Mediterranean diet adherence. Methods: Data from a population-based cohort study of older adults (HEllenic Longitudinal Investigation of Aging and Diet–HELIAD) in Greece were used. Probability of prodromal PD was calculated according to MDS research criteria. A detailed food frequency questionnaire was used to evaluate dietary intake and calculate Mediterranean diet adherence score, ranging from 0 to 55, with higher scores indicating higher adherence. Results: The median probability of prodromal PD was 1.9%, ranging from 0.2 to 96.7% in 1731 PD-free individuals over the age of 65 (41% male). Lower probability for prodromal PD (p<0.001) in the higher Mediterranean diet adherence groups was noted, driven mostly by non-motor markers of prodromal PD, depression, constipation, urinary dysfunction and daytime somnolence. Each unit increase in the Mediterranean diet score was associated with a 2% decreased probability for prodromal PD (p<0.001). Compared to participants in the lowest quartile of Mediterranean diet adherence, those in the highest quartile were associated with a ~21% lower probability for prodromal PD. Conclusions: Adherence to the Mediterranean diet is associated with lower probability of prodromal PD in older people. Further studies are needed to elucidate the potential causality of this association, potential relation of the Mediterranean diet to delayed onset or lower incidence of PD, as well as the underlying neurobiological mechanisms.
Γλώσσα: Αγγλικά
Σελίδες: 10
DOI: 10.1002/mds.27489
EISSN: 1531-8257
Θεματική κατηγορία: [EL] Διατροφή και Διαιτολογία[EN] Nutrition and Dieteticssemantics logo
[EL] Ιατρική και Επιστήμες Υγείας[EN] Medical and Health Sciencessemantics logo
[EL] Νευροεπιστήμες[EN] Neurosciencessemantics logo
Λέξεις-κλειδιά: elderlyMediterraneanneurodegenerationnutritionprodromal
Κάτοχος πνευματικών δικαιωμάτων: © 2018 International Parkinson and Movement Disorder Society
Ηλεκτρονική διεύθυνση του τεκμηρίου στον εκδότη: https://onlinelibrary.wiley.com/doi/10.1002/mds.27489
Ηλεκτρονική διεύθυνση περιοδικού: https://onlinelibrary.wiley.com/journal/15318257
Τίτλος πηγής δημοσίευσης: Movement Disorders
Τεύχος: 1
Τόμος: 34
Σελίδες τεκμηρίου (στην πηγή): 48-57
Σημειώσεις: This study was supported by the following grants: IIRG‐09‐133014 from the Alzheimer's Association; 189 10276/8/9/2011 from the ESPA‐EU program Excellence Grant (ARISTEIA), which is co‐funded by the European Social Fund and Greek National resources, and DY2b/oik.51657/14.4.2009 from the Ministry for Health and Social Solidarity (Greece). Maria I. Maraki and Costas A. Anastasiou have received financial support from the Greek State Scholarships Foundation (MIS: 5001552).
Εμφανίζεται στις συλλογές:Μεταδιδακτορικοί ερευνητές

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4.Maraki et al. Movement Disorders, Vol. 34, No. 1, 2019.pdf
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